New research published in the Proceedings of the National Academy of Sciences suggests that a neurotransmitter commonly used to treat depression and anxiety may actually worsen tinnitus, a frustrating auditory condition.
Tinnitus is characterized by a persistent ringing or buzzing in the ears. While it can be a mild annoyance for some, others experience severe symptoms that lead to significant distress and anxiety. The condition is widespread, affecting up to 14% of people globally, with many cases classified as severe.
In the study, researchers from Oregon Health & Science University and Anhui University in China used a mouse model to examine serotonin’s effects on the brain. Their findings showed that increased serotonin levels were associated with stronger behavioral indicators linked to tinnitus.
Antidepressants and Their Effects on Hearing
The medications in question are selective serotonin reuptake inhibitors (SSRIs), a commonly prescribed class of antidepressants. These drugs are used to treat moderate to severe depression and anxiety by boosting serotonin levels in the brain.